A DNA sequence editor with voice input and output.

Abstract

DNA sequence editors for IBM PC-compatible computers are often line-oriented, with complicated methods of entering and modifying sequences. This paper describes SE, a full-screen sequence editor that is operated like a word processor. Features include keyboard entry of new sequences, ability to search for patterns or sequence features, ability to switch strands, and ability to renumber and rotate circular sequences. The entry of new sequences can be confirmed by a spoken voice, and for proofreading, SE will read a sequence aloud using the PC's speaker. If the computer is fitted with a sound board and speech-recognition software, SE will also allow voice-input of sequences. Sequences are saved on a file in a format that is compatible with most sequence-analysis programs.