PubMed · 788341
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S Tomaszunas. 1976-08-01. [Filariasis].. https://pubmed.ncbi.nlm.nih.gov/788341/
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Studies on the occurrence of early symptoms of filariasis have been conducted in two transmigration Units in the valley of the Wae Apu river, Buru island, Maluku Province, Indonesia. In both Units, higher disease rates were found in areas, where there was a closer contact with positive natives, higher density of the vector mosquito, and higher infective rates in the mosquitoes.
The results of mass treatment using 50 mg diethylcarbamazine per kg body-weight followed one year later by short term selective re-treatment in a highly endemic area of Brugia timori are described. The criteria for selection of re-treatment are simple and practical for use in rural areas. The microfilaria rate by finger prick decreased from 24% to 0 and by Nuclepore filtration from 30% to 2.5%. The disease rates were also affected favourably. 88% of persons receiving the drug reacted to treatment, this percentage slightly exceeding the total filarial infection rate (71%). The prevalence, onset, duration and nature of side reactions are briefly discussed and related to the presence of microfilaraemia and disease manifestations among the study population.