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Poly(ADP-ribose): historical perspective.

T Sugimura·M Miwa
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Abstract

The early historical background of the discovery of poly(ADP-ribose) and the following development of science on poly(ADP-ribose) are reviewed. Fundamental knowledge on the natures of poly(ADP-ribose), poly(ADP-ribose) polymerase and enzymes degrading poly(ADP-ribose) are summarized with brief description on the methodology for their purification and characterization. Future prospect of research on biological significance of poly(ADP-ribose) has also been discussed briefly.

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History, 20th CenturyMolecular StructurePoly Adenosine Diphosphate RiboseHistorical ArticleJournal Article

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T Sugimura, M Miwa. 1994. Poly(ADP-ribose): historical perspective.. https://doi.org/10.1007/bf00928437

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