PubMed · 7910042
The source did not provide an abstract. Follow the original record for more information.
Explore connections, maps & timelines
A Rocino, R de Biasi. 1994. Hemofil-M study.. https://doi.org/10.1007/bf01774535
Cite the original work for its findings. Save a collection to share your selection of sources.
KEEP EXPLORING
The new Quality Control Program in Immunophenotyping for Central Europe (CEQUAL) was created in 1993. Its first formal send-around proficiency exercise, consisting of a stained stabilised preparation of leukocytes, took place in November 1993. Forty-one laboratories from Slovakia, Poland, Hungary, and the Czech Republic participated. Eighty-three percent of member laboratories returned results and list mode files. The results for each cell population were evaluated for central tendencies, variability, and overall distribution patterns. Extreme outliers were identified and list mode files reviewed for clues to the aberrerant values. When found these reasons were communicated back to member labs. When extreme outlier values were removed, all coefficient of variations (CVs) for lymphocyte populations were below 10%, except for NK cells, which had a CV of 14.8%. In future send-arounds, unstained and pathologic specimens will be used. This CEQUAL program is the first to function on such a broad international basis.
The immunological and immunohistochemical characteristics of a patient with nodular lymphoid hyperplasia (NLH) of the terminal ileum were investigated pre- and post-operatively. The patient presented with diarrhea, lower abdominal pain, and weight loss, and an abdominal X-ray following barium enema revealed multiple small nodules in the terminal ileum which were subsequently confirmed to be NLH by histological examination. Preoperatively, although the serum immunoglobulin levels were normal, the T-cell responses in the peripheral blood, including the phytohemagglutinin (PHA)-blastogenesis and the T4/T8 ratio, were impaired. However, following an ileocecal resection, the PHA-blastogenesis became augmented and the T4/T8 ratio recovered to within the normal range. The immunohistochemical findings revealed a more marked accumulation of T cells in the interstitium around the hyperplastic follicles than in the interstitium of the normal intestine.
Explore the source record for details and available documents.