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A computer program for the statistical analysis of repeated event data using a mixed effects regression model.

R Natarajan·B W Turnbull·E H Slate·M T Wells·L C Clark·H Abu-Libdeh
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Abstract

This paper presents a computer program for fitting mixed effects regression models to repeated events data. The method has been described by Abu-Libdeh, Turnbull and Clark (Biometrics 46 (1990) 1017-1034). Such data can occur in longitudinal studies where subjects experience repeated events over time. The program allows the stepwise construction of a series of regression models which can be used to examine and test the influence of the various measured covariates upon the event rates. Two examples are provided. The first is a simple example involving the incidence of mammary tumors in rats. The second involves a very large complex data set from a clinical trial for the prevention of recurrent skin tumors.

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AnimalsMammary Neoplasms, ExperimentalModels, StatisticalRatsRegression AnalysisSoftwareJournal ArticleResearch Support, U.S. Gov't, P.H.S.

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R Natarajan, B W Turnbull, E H Slate, M T Wells, L C Clark, H Abu-Libdeh. 1994. A computer program for the statistical analysis of repeated event data using a mixed effects regression model.. https://doi.org/10.1016/0169-2607(94)90101-5

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