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PubMed · 7958103

[Gene expression and function of progesterone receptor isoforms].

J Kato
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Abstract

Progesterone receptor is unique in terms of the existence of two isoforms of A and B. The isoforms are expressed by two distinct promoters in the peripheral as well as the brain. The 5'-untranslated region and the coding region around ATG 1 of rat progesterone receptor form B as well as the ligand binding domain are cloned. The function of the forms A and B is still unclear. However, it has been reported that the form A is a hormone-dependent transdominant repressor of the B function under certain circumstance of the cell. This model is very interesting to elucidate the molecular mechanism of progesterone action.

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AnimalsBase SequenceBrainGene ExpressionIn Situ HybridizationMiceMolecular Sequence DataRNA, MessengerRatsReceptors, ProgesteroneEnglish AbstractJournal ArticleReview

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BibTeXRIS

J Kato. 1994-08-20. [Gene expression and function of progesterone receptor isoforms].. https://doi.org/10.1507/endocrine1927.70.6_537

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