DNA sequence from Cretaceous period bone fragments.

S R Woodward; N J Weyand; M Bunnell

doi:10.1126/science.7973705

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PubMed · 7973705

DNA sequence from Cretaceous period bone fragments.

S R Woodward·N J Weyand·M Bunnell

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Abstract

DNA was extracted from 80-million-year-old bone fragments found in strata of the Upper Cretaceous Blackhawk Formation in the roof of an underground coal mine in eastern Utah. This DNA was used as the template in a polymerase chain reaction that amplified and sequenced a portion of the gene encoding mitochondrial cytochrome b. These sequences differ from all other cytochrome b sequences investigated, including those in the GenBank and European Molecular Biology Laboratory databases. DNA isolated from these bone fragments and the resulting gene sequences demonstrate that small fragments of DNA may survive in bone for millions of years.

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Animals Base Sequence Bone and Bones Consensus Sequence Cytochrome b Group DNA, Mitochondrial Databases, Factual History, Ancient Molecular Sequence Data Paleontology Polymerase Chain Reaction Sequence Analysis, DNA Sequence Homology, Nucleic Acid Utah Historical Article Journal Article

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S R Woodward, N J Weyand, M Bunnell. 1994-11-18. DNA sequence from Cretaceous period bone fragments.. https://doi.org/10.1126/science.7973705

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