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PubMed · 7979424

[Treatment of prostatic carcinoma with UFT and leucovorin--basic study using SRCA].

K Uchida·T Hayashi·T Shiga·K Hattori·Y Nishijima·S Kasaya·T Shimazui·H Akaza·K Koiso·R Nemoto
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Abstract

Combination effect of UFT and leucovorin against the rat prostatic carcinoma (R-3327) was evaluated by the subrenal capsular assay (SRCA) using nude mice. Anticancer effect of UFT was augmented by co-administration of both low and high dose leucovorin. These results suggest a clinical usefulness of UFT administration with leucovorin for the patients with hormonally refractory advanced prostatic carcinoma.

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AnimalsAntineoplastic Combined Chemotherapy ProtocolsHumansLeucovorinMaleMiceMice, Inbred BALB CMice, NudeProstatic NeoplasmsSubrenal Capsule AssayTegafurTumor Cells, CulturedUracilEnglish AbstractJournal Article

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K Uchida, T Hayashi, T Shiga, K Hattori, Y Nishijima, S Kasaya, T Shimazui, H Akaza, K Koiso, R Nemoto. 1994. [Treatment of prostatic carcinoma with UFT and leucovorin--basic study using SRCA].. https://pubmed.ncbi.nlm.nih.gov/7979424/

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