The magnetization transfer effect in cerebral infarction.

J M Prager; J D Rosenblum; D C Huddle; C K Diamond; C E Metz

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PubMed · 7985569

The magnetization transfer effect in cerebral infarction.

J M Prager·J D Rosenblum·D C Huddle·C K Diamond·C E Metz

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Abstract

PURPOSE: To estimate the age of cerebral infarcts using magnetization transfer. METHODS: Twelve patients with radiographically and clinically documented cortical and subcortical cerebral infarctions underwent MR imaging on a 0.1T magnet. Magnetization transfer contrast images were generated by application of off-resonance pulses to every other repetition time on intermediate-weighted images. The magnetization transfer effect was calculated by obtaining an intensity value in the region of interest within the infarcted area. RESULTS: The data show a pattern in which the magnetization transfer effect decreases as the chronicity of the infarct increases. Infarcts less than 1 week old had an average magnetization transfer effect of 0.35. Those more than 1 week and less than 1 month old average 0.30. Infarcts more than 1 month and specifically those more than 1 year old averaged 0.16 or less. CONCLUSION: Magnetization transfer offers the potential to estimate the age of cerebral infarcts.

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Acute Disease Adult Aged Aged, 80 and over Cerebral Cortex Cerebral Infarction Chronic Disease Female Humans Image Enhancement Magnetic Resonance Imaging Magnetics Male Middle Aged Time Factors Tomography, X-Ray Computed Journal Article

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J M Prager, J D Rosenblum, D C Huddle, C K Diamond, C E Metz. 1994. The magnetization transfer effect in cerebral infarction.. https://pubmed.ncbi.nlm.nih.gov/7985569/

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