PubMed HealthSearch

PubMed · 7992143

Statistical methods for measuring outcomes.

Abstract

This issue of the journal concerns promotion of the routine use of outcome measures in clinical practice; the purpose of this particular article, however, is to warn care providers to think very very carefully before routinely using such measures. Just what are the benefits of their use? What are the outcome measures intended to demonstrate? In order to try to convince the reader that there might be real difficulties in the interpretation of the results, the main body of the paper concentrates on the difficulties in the interpretation of data from a structured research project that has been specifically designed to evaluate an innovation in mental health care provision. The difficulties of interpreting haphazardly collected data as part of routine clinical or administrative practice will be far greater. One of the main purposes of an evaluative exercise is comparison: which approach to service provision is the better? If care providers really want to be involved in mental health service evaluation then their time would be much better spent in taking part in a large multicentre trial.

Explore related subjects

Keep this discovery

Explore connections, maps & timelines

BibTeXRIS

G Dunn. 1994. Statistical methods for measuring outcomes.. https://doi.org/10.1007/bf00796377

Cite the original work for its findings. Save a collection to share your selection of sources.

KEEP EXPLORING

Related citations

[St John's wort against depression in favour again].

Extracts of Hypericum perforatum St. John's wort, have been used since antiquity for the treatment of depressive symptoms. In 25 controlled clinical trials where hypericum extract was compared with placebo and established antidepressants, improvement was obtained in 61 percent of patients on low-dose treatment (< 1.2 mg hypericum extract), and in 75 percent of patients treated with a higher dose (2.7 mg). The side effects were mild and occurred at lower frequency than did those of other antidepressants. The constituent of hypericum extract that is responsible for the antidepressant effect has not been identified. Nor is the mechanism of action known, but a combination of low-grade monoamine oxidase inhibition and noradrenaline and serotonin reuptake blockade seems the most likely alternative, though other interesting mechanisms have also been proposed. Owing to their beneficial effect and low toxicity, preparations containing extracts from H perforatum might furnish an alternative to established therapy, especially among patients concerned about stigmatization or less apprehensive of herbal medication than of synthetic drugs.

Controlled Clinical Trials as Topic