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PubMed · 7998102

Chronic allograft rejection: an update.

P Häyry·S Yilmaz
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Abstract

The aetiology of chronic rejection is most likely multifactorial. The common feature in all organ allografts undergoing chronic rejection is persistent perivascular inflammation and a concentric generalised arteriosclerosis affecting all first and second order intramural arteries. A hypothesis is presented that low-grade damage to the endothelium induces the secretion of growth factors which, in turn, are responsible for smooth muscle cell replication and their influx into intima.

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AnimalsChronic DiseaseGraft RejectionKidney TransplantationModels, BiologicalRatsRats, Inbred StrainsRats, Inbred WFTransplantation, HomologousJournal Article

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P Häyry, S Yilmaz. 1994. Chronic allograft rejection: an update.. https://pubmed.ncbi.nlm.nih.gov/7998102/

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