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PubMed · 8003983

Protein folding dynamics: the diffusion-collision model and experimental data.

M Karplus·D L Weaver
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Abstract

The diffusion-collision model of protein folding is assessed. A description is given of the qualitative aspects and quantitative results of the diffusion-collision model and their relation to available experimental data. We consider alternative mechanisms for folding and point out their relationship to the diffusion-collision model. We show that the diffusion-collision model is supported by a growing body of experimental and theoretical evidence, and we outline future directions for developing the model and its applications.

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DiffusionKineticsMathematicsModels, ChemicalProtein FoldingProtein Structure, SecondaryThermodynamicsJournal ArticleResearch Support, U.S. Gov't, Non-P.H.S.Research Support, U.S. Gov't, P.H.S.Review

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M Karplus, D L Weaver. 1994. Protein folding dynamics: the diffusion-collision model and experimental data.. https://doi.org/10.1002/pro.5560030413

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