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Poly(ADP-ribose) polymerase: a molecular nick-sensor.

G de Murcia·J Ménissier de Murcia
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Abstract

Poly(ADP-ribose) polymerase (PARP) participates in the intricate network of systems developed by the eukaryotic cell to cope with the numerous environmental and endogenous genotoxic agents. Cloning of the PARP gene has allowed the development of genetic and molecular approaches to elucidate the structure and function of this abundant and highly conserved enzyme.

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AnimalsHumansPoly Adenosine Diphosphate RibosePoly(ADP-ribose) PolymerasesRepetitive Sequences, Nucleic AcidJournal ArticleResearch Support, Non-U.S. Gov'tReview

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BibTeXRIS

G de Murcia, J Ménissier de Murcia. 1994. Poly(ADP-ribose) polymerase: a molecular nick-sensor.. https://doi.org/10.1016/0968-0004(94)90280-1

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