How muscle may contract.

G F Elliott; C R Worthington

doi:10.1016/0304-4165(94)90124-4

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PubMed · 8031829

How muscle may contract.

G F Elliott·C R Worthington

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Abstract

A new molecular model is proposed for muscle contraction, that involves the electrical charging of the long (C-terminal) alpha-helical part of the head of the myosin molecule (S1) while the head is attached to actin; as it charges the alpha-helical part moves in the radial electric field between the filaments. The alpha-helical part snaps back when the myosin molecule is discharged electrically, at the moment that ATP binds to the active enzymatic site. This snap-back model explains several puzzling phenomena in contractility, as well as providing a physical explanation for the origin of an impulsive force that drives muscle contraction.

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Actins Adenosine Triphosphate Animals Binding Sites Electromagnetic Fields Models, Biological Models, Molecular Muscle Contraction Muscles Myosins Journal Article Review

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G F Elliott, C R Worthington. 1994-07-06. How muscle may contract.. https://doi.org/10.1016/0304-4165(94)90124-4

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