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Novel 3-beta-methoxysteroids from the Senegalese sponge Microscleroderma spirophora.

V Costantino·E Fattorusso·A Mangoni·M Aknin·E M Gaydou
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Abstract

The Senegalese sponge Microscleroderma spirophora has been found to produce exclusively very unusual 3 beta-methoxysteroids in place of the common 3 beta-hydroxysteroids. Six different methoxysteroids (three of which are novel compounds) have been isolated and identified by spectroscopic means (MS, IR, 1H and 13C NMR), and their taxonomic significance discussed. A new method for the determination of the configuration at C-24 in saturated 24-ethyl side chains is also proposed.

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AnimalsMagnetic Resonance SpectroscopyMass SpectrometryMolecular ConformationMolecular StructurePoriferaSpectrophotometry, InfraredSteroidsJournal ArticleResearch Support, Non-U.S. Gov't

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V Costantino, E Fattorusso, A Mangoni, M Aknin, E M Gaydou. 1994. Novel 3-beta-methoxysteroids from the Senegalese sponge Microscleroderma spirophora.. https://doi.org/10.1016/0039-128x(94)90025-6

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