Controlling chaos in the brain.

S J Schiff; K Jerger; D H Duong; T Chang; M L Spano; W L Ditto

doi:10.1038/370615a0

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Controlling chaos in the brain.

S J Schiff·K Jerger·D H Duong·T Chang·M L Spano·W L Ditto

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Abstract

In a spontaneously bursting neuronal network in vitro, chaos can be demonstrated by the presence of unstable fixed-point behaviour. Chaos control techniques can increase the periodicity of such neuronal population bursting behaviour. Periodic pacing is also effective in entraining such systems, although in a qualitatively different fashion. Using a strategy of anticontrol such systems can be made less periodic. These techniques may be applicable to in vivo epileptic foci.

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Action Potentials Animals Electric Stimulation Female Hippocampus In Vitro Techniques Models, Neurological Nerve Net Nonlinear Dynamics Periodicity Rats Rats, Sprague-Dawley Journal Article Research Support, Non-U.S. Gov't Research Support, U.S. Gov't, Non-P.H.S.Research Support, U.S. Gov't, P.H.S.

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S J Schiff, K Jerger, D H Duong, T Chang, M L Spano, W L Ditto. 1994-08-25. Controlling chaos in the brain.. https://doi.org/10.1038/370615a0

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