Diet and genital warts: a case-control study.

I Bairati; K J Sherman; B McKnight; L A Habel; S K Van den Eeden; A Stergachis; J R Daling

doi:10.1097/00007435-199405000-00004

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PubMed · 8073343

Diet and genital warts: a case-control study.

I Bairati·K J Sherman·B McKnight·L A Habel·S K Van den Eeden·A Stergachis·J R Daling

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Abstract

BACKGROUND AND OBJECTIVES: Clinical observations support a substantial role for impaired immunity in the development of human papillomavirus (HPV) infections. Intake of vitamins, especially vitamins A and C, and alcohol consumption have been reported to influence immune response. GOAL OF THE STUDY: To examine the relationship between nutritional risk factors, including alcohol consumption, and the risk of genital warts. STUDY DESIGN: A case-control study was conducted among enrollees at four clinics of Group Health Cooperative in western Washington state. A total of 188 cases diagnosed with condyloma from April 1, 1987 to September 30, 1991 and 245 controls completed a semi-quantitative food frequency questionnaire. RESULTS: After adjustment for socioeconomic indicators, total energy intake, smoking and sexual behavior, a weekly consumption of two to four alcoholic drinks was associated with an almost doubled risk of genital warts (OR = 1.9, 95% confidence interval [CI] = 1.0-3.6). Consuming five or more alcoholic drinks per week was even more related to the risk of genital warts (OR = 2.4, 95% CI = 1.2-5.1). The risks tended to increase with the number of alcoholic drinks (P = 0.006). Vitamin A and C intakes as measured by a food frequency questionnaire did not alter the risk of condyloma. CONCLUSION: Moderately high consumption of alcohol is associated with increased risk of condyloma. Further biological and epidemiological studies are needed to explain this association.

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Adolescent Adult Alcohol Drinking Ascorbic Acid Case-Control Studies Condylomata Acuminata Diet Female Humans Male Risk Factors Vitamin A Journal Article Research Support, U.S. Gov't, P.H.S.

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I Bairati, K J Sherman, B McKnight, L A Habel, S K Van den Eeden, A Stergachis, J R Daling. Diet and genital warts: a case-control study.. https://doi.org/10.1097/00007435-199405000-00004

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