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PubMed · 8077031

Neonatal necrotizing enterocolitis: a clinical study.

A Narang·R Rao·O N Bhakoo
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Abstract

Necrotizing enterocolitis was found in 77 infants over a 5 year period. Diagnosis of NEC was established on 4.9 + 4.8 days in babies with birth weight of 1667 + 577 grams and the gestational age of 33.3 + 2.6 weeks. Definite disease occurred in 33 (42.9%) babies while there was strong suspicion in another 44 (57.1%) babies. Prefeed gastric residue (98.7%), abdominal distension (97.3%), lethargy (78.7%), hypotonia (60%) and jaundice (48%) were the main presenting features. However, blood in stools and abdominal wall erythema were found in 38.7% babies. About one third of infants had a positive blood culture. Pneumatosis intestinalis was present in 83.9% of babies and pneumoperitoneum was seen in 35.5% of neonates with NEC. Ileo-ceco-colic region was the commonest site of involvement. Overall survival was 61% and survival with Stage III was only 13%. Birth weight less than 1500 g, gestational age less than 32 weeks, erythema of the abdominal wall, intra-abdominal mass, portal venous gas in abdominal X-ray and Gram negative septicemia were associated with higher mortality.

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Age of OnsetBirth WeightCitrobacterEnterocolitis, PseudomembranousEscherichia coliFemaleHumansIndiaInfant, NewbornKlebsiellaMalePerinatologyRadiography, AbdominalRisk FactorsSalmonella typhimuriumSeverity of Illness IndexStaphylococcus aureusStreptococcusSurvival RateJournal Article

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A Narang, R Rao, O N Bhakoo. 1993. Neonatal necrotizing enterocolitis: a clinical study.. https://pubmed.ncbi.nlm.nih.gov/8077031/

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