PubMed · 809063
Excitation-contraction coupling: effects of "zero"-Ca2+ medium.
Abstract
Frog sartorius muscles, exposed for up to 15--20 min to media containing ethylene glycol bis (beta-aminoethyl ether) - N, N'-tetraacetic acid and thus having free Ca2+ concentration less than 10(-8) M, produce isometric contractions with basically normal but speedier latency relaxation and earliest tension development. The excitation-contraction coupling is thus also basically normal, but speedier evidently in respect to release of activator Ca2+ from the sarcoplasmic reticulum.
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A Sandow, M Krishna, D Pagala, E C Sphicas. 1975-09-08. Excitation-contraction coupling: effects of "zero"-Ca2+ medium.. https://doi.org/10.1016/0304-4165(75)90157-9
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