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PubMed · 81164

Modification of the Grimelius and de Grandi method and its value for demonstrating argyrophilia of endocrine polypeptide APUD cells.

R Hohlerová·J Jaklová
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APUD CellsAnimalsEndocrine GlandsHistocytochemistryHumansMicePeptidesRatsSilver NitrateStaining and LabelingJournal Article

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R Hohlerová, J Jaklová. 1978. Modification of the Grimelius and de Grandi method and its value for demonstrating argyrophilia of endocrine polypeptide APUD cells.. https://pubmed.ncbi.nlm.nih.gov/81164/

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PubMed1979

APUD-type recepto-secretory cells in the chicken lung.

The epithelium of the intrapulmonary airways of the chicken lung has been studied by fluorescence and electron microscopy. Numerous intensely yellow-fluorescent cells occur in the epithelium of the primary and secondary bronchi. The cell cytoplasm contains characteristic granular vesicles with an electron-dense central core. The vesicles react positively to chromaffin and argentaffin treatment, indicating that they are possible storage sites for amines. Synapse-like junctions occur between the granular cells and the intraepithelial nerve endings, filled with numerous mitochondria, suggesting that these granular cells may have a dual function as both receptor and endocrine cell.

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