Site-specific recombinases: tools for genome engineering.

N J Kilby; M R Snaith; J A Murray

doi:10.1016/0168-9525(93)90104-p

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Site-specific recombinases: tools for genome engineering.

N J Kilby·M R Snaith·J A Murray

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Abstract

Site-specific recombinases from bacteriophage and yeasts have been developed as novel tools for manipulating DNA both in the test-tube and in living organisms. We discuss the characteristics of these enzyme systems, review their application in genetic and developmental studies and speculate on their future potential for large-scale directed modifications of eukaryotic genomes.

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Animals Base Sequence DNA Nucleotidyltransferases Genetic Engineering Genome Molecular Sequence Data Substrate Specificity Journal Article Research Support, Non-U.S. Gov't Review

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N J Kilby, M R Snaith, J A Murray. 1993. Site-specific recombinases: tools for genome engineering.. https://doi.org/10.1016/0168-9525(93)90104-p

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