PubMed · 8141240
Brief communication: bone remodeling rates: a test of an algorithm for estimating missing osteons.
Abstract
Frost (1987a) proposed an algorithm for estimating the number of missing osteons that correspond to observed osteon population densities (OPD). Such an algorithm should allow more accurate estimates of bone remodeling rates for skeletal remains for which in vivo labeling is not possible. In order to validate the algorithm, it was tested on an autopsy sample of 44 ribs. Estimates of activation frequency (mu RC) and bone remodeling rate (Vf,r,t) using the new algorithm are in reasonable agreement with age-matched tetracycline-based values. Although mean values for activation frequencies (mu RC) and bone formation rate (Vf,r,t) generated by the algorithm were generally lower, they fell below 1 standard error for only an age category that included all ages above the 5th decade. It is now appropriate to apply the algorithm to archaeological skeletal remains.
Explore related subjects
Keep this discovery
Explore connections, maps & timelines
S D Stout, R R Paine. 1994. Brief communication: bone remodeling rates: a test of an algorithm for estimating missing osteons.. https://doi.org/10.1002/ajpa.1330930109
Cite the original work for its findings. Save a collection to share your selection of sources.