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Human endogenous retroviral elements and autoimmunity: data and concepts.

A Perl·K Banki
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Abstract

The human genome contains a complex variety of inherited endogenous retroviral sequences (ERSs), several of which are transcriptionally active and contain open reading frames. Aberrant expression of ERSs and generation of antibodies to ERS-encoded proteins have recently been revealed in autoimmune disorders. Involvement of ERSs could explain both the familial aggregation and the detection of antiretroviral antibodies in autoimmune diseases.

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Autoimmune DiseasesAutoimmunityGenome, HumanHumansModels, GeneticRetroviridaeJournal ArticleResearch Support, Non-U.S. Gov'tResearch Support, U.S. Gov't, P.H.S.

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BibTeXRIS

A Perl, K Banki. 1993. Human endogenous retroviral elements and autoimmunity: data and concepts.. https://doi.org/10.1016/0966-842x(93)90131-a

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