Knowledge-based protein modeling.

M S Johnson; N Srinivasan; R Sowdhamini; T L Blundell

doi:10.3109/10409239409086797

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PubMed · 8143488

Knowledge-based protein modeling.

M S Johnson·N Srinivasan·R Sowdhamini·T L Blundell

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Abstract

Knowledge, both from the three-dimensional structures of homologous proteins and from the general analysis of protein structure, is of value in modeling a protein of known sequence but unknown structure. While many models are still constructed at least in part by manual methods on graphics devices, automated procedures have come into greater use. These procedures include those that assemble fragments of structure from other known structures and those that derive coordinates for the model from the satisfaction of restraints placed on atomic positions.

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Amino Acid Sequence Animals Humans Models, Molecular Molecular Sequence Data Protein Conformation Protein Engineering Proteins Sequence Alignment Software Journal Article Research Support, Non-U.S. Gov't Review

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M S Johnson, N Srinivasan, R Sowdhamini, T L Blundell. 1994. Knowledge-based protein modeling.. https://doi.org/10.3109/10409239409086797

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