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PubMed · 8143793

Structure and function of RecA-DNA complexes.

A Stasiak·E H Egelman
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Abstract

While the E. coli RecA protein has been the most intensively studied enzyme of homologous recombination, the unusual RecA-DNA filament has stood alone until very recently. It now appears that this protein is part of a universal family that spans all of biology, and the filament that is formed by the protein on DNA is a universal structure. With RecA's role in recombination given new and greatly increased significance, we focus in this review on the energetics of the RecA-mediated strand exchange and the relation between the energetics and recombination spanning heterologous inserts.

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Adenosine TriphosphateDNADNA, Single-StrandedDeoxyribonucleoproteinsModels, MolecularRec A RecombinasesRecombination, GeneticJournal ArticleResearch Support, Non-U.S. Gov'tReview

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A Stasiak, E H Egelman. 1994-03-15. Structure and function of RecA-DNA complexes.. https://doi.org/10.1007/bf01924002

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