PubMed · 8151219
The source did not provide an abstract. Follow the original record for more information.
Explore connections, maps & timelines
E Cataldo, H S Santis. 1993. A clinico-pathologic presentation. Hyperostosis.. https://pubmed.ncbi.nlm.nih.gov/8151219/
Cite the original work for its findings. Save a collection to share your selection of sources.
KEEP EXPLORING
Tooth eruption is an essential process for the survival of many different species and although the movement of teeth into function has been the subject of extensive research there is no consensus as to the mechanisms involved. Recent understanding of the mechanisms of cell activation and regulation has widened the scope for further research at the molecular level. This paper reviews the evidence for an eruptive force, its direction and source. The relationships between the eruptive force and molecular mechanisms of cell activation remain to be determined.
For quantitative evaluation of the different imaging quality of cephalograms and computed tomography in the region of the lower incisors, the macroscopic and histological findings of specimens were compared with the corresponding radiological findings. After removal of the soft tissue from 11 mandibular dentate segments, 15 artificial bone defects of different dimensions were produced in the region of the lower incisors. In comparison with the microscopic jaw measurements, the mean labiolingual diameter of the frontal alveolar process of the single incisors was overestimated in the cephalograms by 0.3 to 1.2 mm. Most of the anatomical-radiological correlations of the cephalometric measurements was insignificant. Individual metric assessment of the labiolingual bone width or of the facial/lingual cortical bone plates or the identification of the artificial defects of lower incisors in the cephalograms were generally not possible. In the CT-images the mean labiolingual diameter of the frontal alveolar process of the single incisors was overestimated by 0.1 to 0.5 mm, but the correlations were highly significant. The facial/lingual cortical bone plates of the lower incisors were evaluated and measured in the CT-scans. Thirteen of 15 artificial bone defects (80%) were identified in the CT-scans. CT-scanning is the only imaging technique offering three-dimensional quantitative evaluation of the labiolingual alveolar bone width and the facial/lingual cortical bone plates.
Mandibular first molar tooth germs were dissected from Mus musculus (CDI) and Mus caroli (age range: 14-day embryo to 1-day postnatal). Most of the tooth germs were separated enzymically into epithelial and mesenchymal components. Interspecific tissue recombinations and intact M. caroli tooth germs were grown in the anterior chamber of the eye of adult CDI mice for 24 weeks. Recombinations of M. caroli enamel-organ epithelium with M. musculus, dental papilla and follicle mesenchyme developed into normal teeth with advanced root, periodontal ligament and bone formation, thereby confirming extensive epithelial-mesenchymal interactions across the species barrier. Labelling sections by in situ hybridization with a M. musculus-specific DNA probe (pMSat5) showed that almost all cells in the pulp, periodontal ligament and bone were M. musculus, including cementoblasts. Reduced enamel epithelium and epithelial cell rests derived from donor M. caroli enamel organ were unlabelled. This indicates that any cementogenic role of Hertwig's epithelial root sheath must be short-lived. The immunological privilege of the intraocular transplantation site in M. musculus CDI mice did not extend to grafts including xenogeneic M. caroli dental mesenchyme. Thus, intact M. caroli tooth germs and recombinations of M. musculus enamel organ with M. caroli dental papilla and follicle showed limited development, with no root formation, and were populated almost exclusively with labelled host M. musculus lymphocytes.