Cell signalling and motile activity.

A W Heldman; P J Goldschmidt-Clermont

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PubMed · 8165573

Cell signalling and motile activity.

A W Heldman·P J Goldschmidt-Clermont

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Abstract

The actin cytoskeleton is a remarkably dynamic structure in non-muscle cells which responds to cell stimulation by a variety of cytokines. A paradigm for such cytokine-induced reorganization of the actin superstructure is the actin response to growth factor of the EGF/PDGF family. This paper reviews the role of the polyphosphoinositide-metabolism, small GTP-binding proteins and profilin in the reorganization of the actin cytoskeleton in cells activated by growth factors.

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Actins Animals Cell Communication Cell Movement Contractile Proteins Cytokines Cytoskeleton GTP-Binding Proteins Microfilament Proteins Profilins Journal Article Research Support, Non-U.S. Gov't Review

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A W Heldman, P J Goldschmidt-Clermont. 1993. Cell signalling and motile activity.. https://pubmed.ncbi.nlm.nih.gov/8165573/

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