Activity oscillations predicted for pyruvate dehydrogenase complexes.

V A Selivanov; D T Zakrzhevskaya; B N Goldstein

doi:10.1016/0014-5793(94)00425-0

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Activity oscillations predicted for pyruvate dehydrogenase complexes.

V A Selivanov·D T Zakrzhevskaya·B N Goldstein

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Abstract

A kinetic model for the pyruvate dehydrogenase complex is analyzed. The model takes into account intermediate channeling through the lipoyl network attached to the complex core, as well as inter-related regulatory effects of protein X acetylation and enzyme phosphorylation. The model predicts undamped oscillations of enzyme activity.

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Kinetics Mathematics Models, Theoretical Oscillometry Pyruvate Dehydrogenase Complex Time Factors Journal Article

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V A Selivanov, D T Zakrzhevskaya, B N Goldstein. 1994-05-30. Activity oscillations predicted for pyruvate dehydrogenase complexes.. https://doi.org/10.1016/0014-5793(94)00425-0

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