Endothelium-derived contracting factors.

P J Lin; P J Pearson; C H Chang

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PubMed · 8221287

Endothelium-derived contracting factors.

P J Lin·P J Pearson·C H Chang

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Abstract

In the past decade, the importance of endothelium in modulating vascular tone has become apparent. Endothelium can produce different vasodilators, such as prostacyclin, endothelium-derived relaxing factor (most likely nitric oxide), and endothelium-derived hyperpolarizing factor. Endothelium can also produce endothelium-derived contracting factors (EDCF) which can induce constriction of the underlying vascular smooth muscle. Constriction may be mediated by a variety of products released by the endothelium. Thus, by responding to various stimuli and releasing either relaxing or contracting factors, the endothelium can set and modulate vascular tone.

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Animals Calcium Endothelins Endothelium, Vascular Humans Hypoxia Nitric Oxide Superoxides Vasoconstriction Journal Article Review

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P J Lin, P J Pearson, C H Chang. 1993. Endothelium-derived contracting factors.. https://pubmed.ncbi.nlm.nih.gov/8221287/

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