Two computer programs using logit transformation for the analysis of S-shaped curves.

E Rieger; J J Bijl; M Rieger

doi:10.1016/0010-4825(93)90136-o

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Two computer programs using logit transformation for the analysis of S-shaped curves.

E Rieger·J J Bijl·M Rieger

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Abstract

Two BASIC computer programs using logit transformation for the analysis of S-shaped curves are presented. The first program estimates the median effective dose (ED50) of drugs. A maximum likelihood method similar to Finney's algorithm of probit analysis is applied. The second fits S-shaped curves to empirical data which cannot be transformed easily to proportions. Logit transformation proves to be a simple and accurate alternative to probit transformation when computing memory is limited or calculation speed is critical.

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Algorithms Computer Systems Data Interpretation, Statistical Dose-Response Relationship, Drug Logistic Models Pharmaceutical Preparations Software Software Design Journal Article

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BibTeX RIS

E Rieger, J J Bijl, M Rieger. 1993. Two computer programs using logit transformation for the analysis of S-shaped curves.. https://doi.org/10.1016/0010-4825(93)90136-o

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