A ureteral small cell carcinoma mixed with malignant mesodermal and ectodermal elements: a clinicopathological, morphological and immunohistochemical study.

M Tsutsumi; M Kamiya; M Sakamoto; K Tobisu; T Kakizoe

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PubMed · 8230759

A ureteral small cell carcinoma mixed with malignant mesodermal and ectodermal elements: a clinicopathological, morphological and immunohistochemical study.

M Tsutsumi·M Kamiya·M Sakamoto·K Tobisu·T Kakizoe

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Abstract

A 60-year-old male with a small cell carcinoma of the right lower ureter is presented. The tumor mainly comprised a small cell carcinoma but also included a full variety of histological types such as transitional cell carcinoma, squamous cell carcinoma, adenocarcinoma, leiomyosarcoma and chondrosarcoma. Immunohistochemical staining was positive for neuron specific enolase and cluster 1 small cell lung cancer antigen/N-CAM in the small cell carcinoma and S-100 in the chondrosarcoma component. The patient underwent a right nephroureterectomy, and received prophylactic radiation of the pelvic and para-aortic lymph node regions and cisplatin and etoposide combination chemotherapy. Eight months after the chemotherapy, a transitional cell carcinoma was found in the bladder neck, and a cystectomy with urethrectomy performed. To our knowledge, this is the second report of a small cell carcinoma originating from the ureter.

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Biomarkers Carcinoma, Small Cell Carcinosarcoma Ectoderm Humans Immunohistochemistry Male Mesoderm Middle Aged Ureteral Neoplasms Case Reports Journal Article

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M Tsutsumi, M Kamiya, M Sakamoto, K Tobisu, T Kakizoe. 1993. A ureteral small cell carcinoma mixed with malignant mesodermal and ectodermal elements: a clinicopathological, morphological and immunohistochemical study.. https://pubmed.ncbi.nlm.nih.gov/8230759/

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