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PubMed · 8231677

Dynamic imaging with T2* contrast using U-FLARE.

D G Norris·M Hoehn-Berlage·F Wittlich·T Back·D Leibfritz
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Abstract

Dynamic changes in T2* in the rat brain induced by the injection of Gd-DTPA are monitored using the U-FLARE sequence. Sensitivity to T2* is easily introduced into this sequence and may be freely varied. The images obtained display an adequate spatial resolution and contrast, for a temporal resolution of 1 s. Intensity-time curves and parametric images of regional cerebral blood flow (rCBV) are presented for three different blood pCO2 values. The results presented clearly demonstrate that U-FLARE is a viable method for dynamically measuring changes in T2*, and thus has application in imaging of both perfusion and functional activation.

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AnimalsBrainCerebrovascular CirculationContrast MediaGadolinium DTPAMagnetic Resonance SpectroscopyOrganometallic CompoundsPentetic AcidRatsJournal ArticleResearch Support, Non-U.S. Gov't

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D G Norris, M Hoehn-Berlage, F Wittlich, T Back, D Leibfritz. 1993. Dynamic imaging with T2* contrast using U-FLARE.. https://doi.org/10.1016/0730-725x(93)90210-5

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