[Neurotransplantations: experimental studies].

J Dymecki

PubMed · 8232738

[Neurotransplantations: experimental studies].

Abstract

Before the intracerebral transplantations of adrenal medulla and fetal substantia nigra in parkinsonian patients were introduced to restore the dopamine deficit, many intensive experimental studies were performed during the last decades. The history of these experiments was presented including the animal models of Parkinson's disease, different implantation techniques and the effects of neurotransplantations of adrenal medulla and fetal substantia nigra obtained in experimental animals. Different mechanisms underlying the transplant-induced functional effects as well as the methods of its stimulation to extend the graft survival and function were described. The ability of intracerebral transplantations to ameliorate the symptoms in animal models of disorders other than Parkinson's disease is also discussed.

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Adrenal Medulla Animals Brain Brain Tissue Transplantation Female Humans Male Parkinson Disease Receptors, Dopamine Substantia Nigra English Abstract Journal Article Review

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J Dymecki. [Neurotransplantations: experimental studies].. https://pubmed.ncbi.nlm.nih.gov/8232738/

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