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PubMed · 8234927

Recent developments in alcoholism:biobehavioral correlates.

D V Gauvin·E Y Cheng·F A Holloway
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Abstract

A literature review was conducted from 1940 through 1992 on the general topic of alcohol-induced hangover. We focused on the physiological, behavioral, and performance decrements demonstrated hours after a physiologically relevant dose of alcohol was administered in both humans and animals. The purpose of this report was threefold: (1) to review and report both previously published and new data from our laboratory concerning the "after effects" of acute high-dose alcohol administration; (2) to highlight the similarities between and usefulness of data generated from both human and animal studies; and (3) to propose that the hangover phenomenon may be the result of one of the three following hypotheses: (a) an opponent-process physiological rebound from alcohol's immediate, intoxicating effects, (b) some toxic reaction to alcohol or its metabolic by-products, or (c) to the circadian dysrhythmia induced by the immediate intoxicating effects of alcohol.

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Alcohol DrinkingAlcoholic IntoxicationAnimalsArousalBrainEthanolFemaleHumansMaleNeurologic ExaminationSubstance Withdrawal SyndromeJournal ArticleReview

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D V Gauvin, E Y Cheng, F A Holloway. 1993. Recent developments in alcoholism:biobehavioral correlates.. https://pubmed.ncbi.nlm.nih.gov/8234927/

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