[Laparoscopic cystoplasty].

E Sánchez de Badajoz; A Mate Hurtado; A Jiménez Garrido; J M Gutiérrez de la Cruz

Home/Archive/PubMed

PubMed · 8239739

[Laparoscopic cystoplasty].

E Sánchez de Badajoz·A Mate Hurtado·A Jiménez Garrido·J M Gutiérrez de la Cruz

View original source ↗Export metadata ↓

Abstract

An endoscopic cystoplasty technique is described for the first time herein. The foregoing was performed in a patient with a previous right nephrectomy due to genitourinary tuberculosis and a microbladder with marked dilatation of the ureter. The procedure commences with the insertion of a 10 mm trocar through the umbilicus and a 12 mm trocar through each flank at the level of the umbilicus and a 5 mm trocar is placed in each iliac fossa. The peritoneum is divided and the bladder wall is dissected free up to the pelvic floor. The ureter is then dissected and cut as low down as possible. A minilaparotomy is performed and the ureter and a loop of intestine are brought out. A segment of the intestine is isolated and continuity is reestablished. The ureter is anastomosed to the isolated intestinal segment and reinserted. The isolated intestinal segment is placed around the bladder and fixed with one suture on each side. A small incision is made in the bladder dome and a similar incision is made very close to this one in the intestinal segment. An Endo-GIA device is inserted, with the narrow portion in the intestine and the larger one in the bladder, and fired twice for each side. Finally, a Roticulator-type stapling device is inserted through the small laparotomy incision and positioned in the precise angle. The stapling device is opened, the bladder and intestinal orifices are positioned and stapled, which completes the procedure.(ABSTRACT TRUNCATED AT 250 WORDS)

Explore related subjects

Humans Laparoscopy Male Tuberculosis, Urogenital Urinary Bladder Diseases Case Reports English Abstract Journal Article

Keep this discovery

Explore connections, maps & timelines

BibTeX RIS

E Sánchez de Badajoz, A Mate Hurtado, A Jiménez Garrido, J M Gutiérrez de la Cruz. 1993. [Laparoscopic cystoplasty].. https://pubmed.ncbi.nlm.nih.gov/8239739/

Cite the original work for its findings. Save a collection to share your selection of sources.

KEEP EXPLORING

Related citations

PubMed2027

Global Genomic Surveillance.

Global genomic surveillance has emerged as a foundational pillar of public health in the twenty-first century, enabling real-time tracking of pathogen evolution and informing outbreak response. This chapter examines the strategic architecture of global genomic surveillance, focusing on its application to arboviruses such as chikungunya virus (CHIKV). It explores the integration of genomic data with epidemiological, clinical, and environmental information within a One Health framework, while addressing critical challenges in governance, equity, and interoperability. The discussion covers the entire genomic surveillance workflow, from sample collection and sequencing to bioinformatic analysis and phylogenetic inference, and highlights the transformative role of artificial intelligence (AI) in predictive surveillance. By analyzing global initiatives, operational barriers, and emerging technologies, this chapter underscores the necessity of sustainable, equitable, and interoperable genomic systems to proactively address current and future infectious disease threats.

Humans↗

PubMed2027

Systematic Dissection of Key Driver Perturbation Signatures in Single Cells via ECCITE-seq.

CRISPR screens, such as expanded CRISPR-compatible cellular indexing of transcriptomes and epitopes by sequencing (ECCITE-seq), enable the simultaneous measurement of transcriptomes, gRNA identity, and cell-surface protein expression at single-cell resolution to systematically interrogate gene function. This platform provides a powerful and scalable experimental approach for validating disease-associated regulators identified by large-scale association studies and other computational methods, including network-based analyses of multi-omics data. Here, as an example application, we describe an ECCITE-seq framework to characterize the transcriptomic consequences of perturbing multiple neuronal key driver genes associated with Alzheimer's disease (AD) in human-induced pluripotent stem cell (hiPSC)-derived neurons. More broadly, by integrating customized pooled gRNA libraries with different CRISPR effectors across multiple cell types, this approach allows for the assessment of the regulatory impact of candidate genes implicated in development and disease processes.

Humans↗

PubMed2027

Identification of Genome-Wide Chromatin Structural Aberration in Cancer by Hi-C Analysis.

Aberrant three-dimensional genome organization is a hallmark of cancer, often driving oncogene activation through mechanisms such as enhancer hijacking. High-throughput chromosome conformation capture (Hi-C) maps these interactions on a genome-wide scale. Unlike earlier dilution-based methods, in situ Hi-C performs proximity ligation within intact nuclei, minimizing random ligation noise and enabling fine-scale structure detection. This chapter describes an optimized in situ Hi-C protocol tailored for cancer cell lines using MboI digestion and biotin-mediated pull-down to generate high-complexity libraries. We further outline a computational workflow that extends beyond standard topological mapping of compartments and topologically associating domains to identify cancer-specific aberrations. Specifically, we focus on detecting chromosomal rearrangements (structural variants) and characterizing the distinct circular topology of extrachromosomal DNA. This integrated experimental and analytical framework provides the necessary tools to dissect the spatial dysregulation underlying tumor evolution.

Humans↗