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PubMed · 8247809

DNA cleavage by benzidine derivatives in weak acidic conditions.

R Yamashita·T Namihira·Y Nakamura
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Abstract

A plasmid DNA was cleaved by aromatic amines in weak acidic conditions at 37 degrees C. The cleavage was not inhibited by 4 hydroxylradical scavengers, EDTA, SOD and catalase. It was strongly influenced by the pH value of the reaction buffer. The decrease of Form I DNA in this reaction obeyed good first-order kinetics.

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AminesBenzidinesCatalaseDNAEdetic AcidFree Radical ScavengersHydrogen-Ion ConcentrationHydrolysisHydroxyl RadicalKineticsPlasmidsSuperoxide DismutaseJournal Article

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R Yamashita, T Namihira, Y Nakamura. 1993. DNA cleavage by benzidine derivatives in weak acidic conditions.. https://pubmed.ncbi.nlm.nih.gov/8247809/

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