Periventricular heterotopia and epilepsy.

P R Huttenlocher; S Taravath; S Mojtahedi

doi:10.1212/wnl.44.1.51

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PubMed · 8290091

Periventricular heterotopia and epilepsy.

P R Huttenlocher·S Taravath·S Mojtahedi

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Abstract

We report a family with nodular subependymal masses of heterotopic gray matter occurring in six members in four generations. Only female members of the family are affected, and there is a high rate of spontaneous abortion, consistent with X-linked dominant inheritance, and lack of viability in affected males. Both in this family and in sporadic cases of subependymal heterotopias there is a high frequency of convulsive disorders, suggesting that epilepsy may be the major clinical manifestation of this developmental defect.

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Abortion, Spontaneous Adult Aged Cerebral Ventricle Neoplasms Cerebrovascular Disorders Child, Preschool Choristoma Epilepsy Female Humans Magnetic Resonance Imaging Male Middle Aged Pedigree Pregnancy Case Reports Journal Article Research Support, Non-U.S. Gov't

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P R Huttenlocher, S Taravath, S Mojtahedi. 1994. Periventricular heterotopia and epilepsy.. https://doi.org/10.1212/wnl.44.1.51

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