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ANCA and IgG subclasses.

M Segelmark·J Wieslander
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Abstract

We studied IgG subclass distribution of ANCA in 247 patients with ELISA. We used monoclonal subclass specific antibodies and purified MPO and proteinase 3 as antigen. We found that IgG1 and IgG4 yield high values in both groups. We also found that high IgG2 titers were rare among the anti-proteinase 3 positive, while it was common among anti-MPO sera. In the assays for IgG3 the situation was the opposite.

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Antibodies, Antineutrophil CytoplasmicAntibodies, MonoclonalAntigensAutoantibodiesEnzyme-Linked Immunosorbent AssayFemaleHumansImmunoglobulin GMaleMiddle AgedMyeloblastinPeroxidaseSerine EndopeptidasesVasculitisJournal Article

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M Segelmark, J Wieslander. 1993. ANCA and IgG subclasses.. https://doi.org/10.1007/978-1-4757-9182-2_10

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