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PubMed · 831279

Lateral diffusion in planar lipid bilayers.

P F Fahey·D E Koppel·L S Barak·D E Wolf·E L Elson·W W Webb
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Abstract

Direct measurements by fluorescence correlation spectroscopy of lateral diffusion coefficients of fluorescent lipid analogs in lipid bilaryer membranes indicate self-diffusion coefficients D greater than 10(-7) square centimeters per second for various lipid systems above their reported transition temperatures. Cholesterol in egg lecithin at mole ratio of 1 : 2 reduces D by about twofold, while retained hydrocarbon solvent can increase it by two- to threefold.

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CholesterolDiffusionGlyceridesIn Vitro TechniquesMembrane LipidsPhosphatidylcholinesSpectrometry, FluorescenceStructure-Activity RelationshipTemperatureJournal ArticleResearch Support, U.S. Gov't, Non-P.H.S.Research Support, U.S. Gov't, P.H.S.

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P F Fahey, D E Koppel, L S Barak, D E Wolf, E L Elson, W W Webb. 1977-01-21. Lateral diffusion in planar lipid bilayers.. https://doi.org/10.1126/science.831279

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