Human cDNA encoding DnaJ protein homologue.

S Oh; A Iwahori; S Kato

doi:10.1016/0167-4781(93)90104-l

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Human cDNA encoding DnaJ protein homologue.

S Oh·A Iwahori·S Kato

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Abstract

We have cloned a cDNA encoding a DnaJ-like protein from the human fibrosarcoma HT-1080 cDNA library. This cDNA encodes a protein of 397 amino acid residues whose sequence shows 38.2% identity with the Escherichia coli DnaJ protein and 47.2% with the yeast DnaJ homologue along the entire length. Since the sequence contains the N-terminal domain region conserved in DnaJ family members and the four repeats of the Cys-X-X-Cys-X-Gly-X-Gly motif which are characteristic of DnaJ proteins, we conclude that this cDNA clone encodes the human homologue of DnaJ.

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Amino Acid Sequence Bacterial Proteins Base Sequence Cell Line Escherichia coli Escherichia coli Proteins Fungal Proteins HSP40 Heat-Shock Proteins Heat-Shock Proteins Humans Molecular Sequence Data Saccharomyces cerevisiae Saccharomyces cerevisiae Proteins Sequence Alignment Tumor Cells, Cultured Comparative Study Journal Article

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S Oh, A Iwahori, S Kato. 1993-07-18. Human cDNA encoding DnaJ protein homologue.. https://doi.org/10.1016/0167-4781(93)90104-l

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