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PubMed · 8347299

Antigen-presenting cell types.

S C Knight·A J Stagg
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Abstract

Different antigen-presenting cells elicit responses in different T-cell populations for primary activation, secondary stimulation and cytotoxic effector functions. Maturing bone marrow derived dendritic cells may acquire and process antigens, transport them to lymph nodes and activate naive T cells located there. By contrast, follicular dendritic cells, acquiring antigen-antibody complexes, maintain 'memory' via B-cell activation. Effector memory T cells recognize various tissue cells bearing antigen and we speculate that they may also target specialized antigen-presenting dendritic populations.

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AnimalsAntigen-Presenting CellsAntigensAntigens, CDBone Marrow CellsCell MovementCytotoxicity, ImmunologicDendritic CellsHLA-D AntigensHistocompatibility Antigens Class IHumansImmunologic MemoryKiller Cells, NaturalLymph NodesLymphocyte ActivationMacrophagesMiceRatsT-Lymphocytes, CytotoxicJournal ArticleReview

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S C Knight, A J Stagg. 1993. Antigen-presenting cell types.. https://doi.org/10.1016/0952-7915(93)90056-x

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