Transgenesis in chickens.

M M Perry; H M Sang

doi:10.1007/bf01972605

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PubMed · 8353531

Transgenesis in chickens.

M M Perry·H M Sang

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Abstract

The application of transgenic technology to domestic poultry offers an alternative means to conventional practice for improvement of this highly productive agricultural species. The hen's reproductive system has unique characteristics which have imposed limitations on the use of established methods for artificial gene transfer. In this article, we review the various strategies that have been adopted to overcome the problem. Target sites for gene insertion include the fertilized ovum, the blastodermal embryo in the unincubated egg, and the primordial germ cells. Notable success in obtaining somatic and germline transformation has been achieved with the use of retroviral vectors to infect the blastodermal embryo. Current attempts to introduce DNA directly into the genome, without resort to pathogen-derived vectors, are discussed.

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Animals Animals, Genetically Modified Blastoderm Breeding Chick Embryo Chickens Genetic Vectors Germ Cells Stem Cells Transfection Journal Article Review

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M M Perry, H M Sang. 1993. Transgenesis in chickens.. https://doi.org/10.1007/bf01972605

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