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PubMed · 8365128

A standard protocol for phototoxicity testing. Results from an interlaboratory study.

R Nilsson·T Maurer·N Redmond
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Abstract

Based on experience accumulated in a number of laboratories, a standardized protocol for phototoxicity testing in experimental animals by the dermal route is presented. By conducting a limited interlaboratory study, demonstrating a high degree of consistency using 8-methoxypsoralen (8-MOP) and acridine, the sensitivity and reproducibility of the proposed methodology is demonstrated. Important aspects of performing phototoxicity testing are discussed.

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AcridinesAdministration, CutaneousAnimalsClinical ProtocolsDermatitis, PhototoxicGuinea PigsMaleMethoxsalenRadiation DosageRadiation Injuries, ExperimentalSkin TestsJournal ArticleResearch Support, Non-U.S. Gov't

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BibTeXRIS

R Nilsson, T Maurer, N Redmond. 1993. A standard protocol for phototoxicity testing. Results from an interlaboratory study.. https://doi.org/10.1111/j.1600-0536.1993.tb03433.x

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