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PubMed · 8379950

Conditional cell ablation in Drosophila.

J W Sentry·M M Yang·K Kaiser
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Abstract

Targeting of cell ablation agents under the control of tissue-specific promoters promises to be an important tool for studies of development and function in higher organisms. Temperature-sensitive cell ablation agents, recently developed for Drosophila, extend control to temporal as well as spatial aspects of toxin expression. Here we discuss achievements to date, together with a novel form of enhancer trap technology with the potential for driving toxin expression in a large range of cell types.

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AnimalsCell DeathDiphtheria ToxinDrosophila ProteinsDrosophila melanogasterEmbryonic and Fetal DevelopmentEye ProteinsGene Expression RegulationGenes, InsectGenes, SuppressorGenetic TechniquesMembrane GlycoproteinsMorphogenesisOrgan SpecificityPhotoreceptor CellsPromoter Regions, GeneticReceptor Protein-Tyrosine KinasesRecombinant Fusion ProteinsRhodopsinRicinJournal Article

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J W Sentry, M M Yang, K Kaiser. 1993. Conditional cell ablation in Drosophila.. https://doi.org/10.1002/bies.950150710

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