Complete nucleotide sequence of the cDNA encoding rabbit coagulation factor VII.

A B Brothers; B J Clarke; W P Sheffield; M A Blajchman

doi:10.1016/0049-3848(93)90048-s

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Complete nucleotide sequence of the cDNA encoding rabbit coagulation factor VII.

A B Brothers·B J Clarke·W P Sheffield·M A Blajchman

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Abstract

Rabbit coagulation factor VII cDNA has been cloned and sequenced. Two rabbit liver cDNA libraries in lambda gt11 were screened using both random-primed, 32p-labelled, factor VII cDNAs and polymerase chain reaction technology. Three overlapping cDNA clones were isolated comprising a sequence of 1572 base pairs of DNA encoding an open-reading-frame of 443 amino acids. Mature circulating rabbit factor VII is predicted to contain 404 amino acids, two less than its human counterpart and three less than bovine factor VII.

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Amino Acid Sequence Animals Base Sequence Cloning, Molecular DNA DNA Restriction Enzymes DNA, Viral Factor VII Molecular Sequence Data Rabbits Journal Article Research Support, Non-U.S. Gov't

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A B Brothers, B J Clarke, W P Sheffield, M A Blajchman. 1993-01-15. Complete nucleotide sequence of the cDNA encoding rabbit coagulation factor VII.. https://doi.org/10.1016/0049-3848(93)90048-s

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