PubMed · 8396475
Chloride channels.
Abstract
Cl- channels have various functions such as regulation of cell volume, transepithelial transport, and control of excitability in nerve and muscle. Several different structural classes of Cl- channels have been identified recently by molecular cloning. The importance of these different classes of Cl- channels can be seen from the inherited diseases resulting from mutations in some of the genes encoding them. Mutagenesis studies are beginning to shed light on their structure-function relationships.
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T J Jentsch. 1993. Chloride channels.. https://doi.org/10.1016/0959-4388(93)90123-g
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