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Refined algorithm and computer program for calculating all non-negative fluxes admissible in steady states of biochemical reaction systems with or without some flux rates fixed.

R Schuster·S Schuster
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Abstract

A refined algorithm together with a computer procedure for determining the complete set of non-negative, steady-state fluxes in biochemical reaction systems of any complexity, with or without some flux rates fixed, is given. It is shown that this set is a convex polyhedron, which may or may not be bounde. The algorithm is illustrated by several examples; one of them concerns intermediary metabolism. A computer code in standard C is presented.

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AlgorithmsBiochemical PhenomenaBiochemistryModels, BiologicalProgramming LanguagesSoftwareJournal ArticleResearch Support, Non-U.S. Gov't

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R Schuster, S Schuster. 1993. Refined algorithm and computer program for calculating all non-negative fluxes admissible in steady states of biochemical reaction systems with or without some flux rates fixed.. https://doi.org/10.1093/bioinformatics%2F9.1.79

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