Diagnostic effectiveness of biochemical liver-function tests, as evaluated by discriminant function analysis.

P P Sher

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PubMed · 844156

Diagnostic effectiveness of biochemical liver-function tests, as evaluated by discriminant function analysis.

P P Sher

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Abstract

I evaluated the diagnostic value of routinely ordered liver-function tests in 175 biopsy-proven cases of hepatic disease by use of stepwise discriminant analysis. The tests studied-total and "direct" bilirubin, alkaline phosphatase, lactate dehydrogenase, and aspartate aminotransferase-correctly classified 45-73% of cases, depending on the homogeneity of the diagnostic groups. Aspartate aminotransferase and alkaline phosphatase were the best discriminators. When all tests were used in the most homogeneous groups (tumors, cirrhosis, and hepatitis), there was a stepwise improvement in diagnostic accuracy from 51 to 73%.

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Alkaline Phosphatase Aspartate Aminotransferases Bilirubin Biopsy Fatty Liver Hepatitis Humans L-Lactate Dehydrogenase Liver Cirrhosis Liver Diseases Liver Function Tests Liver Neoplasms Statistics as Topic Journal Article

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P P Sher. 1977. Diagnostic effectiveness of biochemical liver-function tests, as evaluated by discriminant function analysis.. https://pubmed.ncbi.nlm.nih.gov/844156/

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