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Temperature changes associated with forebrain ischemia in the gerbil.

F Colbourne·S M Nurse·D Corbett
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Abstract

Changes in brain temperature during and following ischemia have not been systematically examined in the gerbil. In this study, gerbils were subjected to a 5-min bilateral carotid artery occlusion. During surgery, skull and body temperatures were maintained with a heated water blanket and a homeothermic blanket unit, respectively. Rectal, skull and brain temperatures were monitored throughout ischemia and for up to 3 h in the post-ischemic period. Intra-ischemic brain temperature fell by approximately 1.5 degrees C even though skull and rectal temperatures remained at normal values. Since brain temperature modulates the extent of ischemic injury it may not be sufficient to rely on skull and/or rectal temperature readings, especially during periods of anesthesia.

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AnimalsBody TemperatureBrainCarotid Artery, CommonFemaleGerbillinaeIschemic Attack, TransientJournal ArticleResearch Support, Non-U.S. Gov't

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F Colbourne, S M Nurse, D Corbett. 1993-02-05. Temperature changes associated with forebrain ischemia in the gerbil.. https://doi.org/10.1016/0006-8993(93)90691-f

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