Current and future trends in immunization against meningitis.

D M Jones

doi:10.1093/jac/31.suppl_b.93

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Current and future trends in immunization against meningitis.

D M Jones

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Abstract

The progress in vaccines for Haemophilus influenzae type b infection is followed; it is the disadvantages of pure polysaccharide vaccines that have stimulated the development of the present generation of polysaccharide-protein conjugated vaccines. From extensive clinical trials it is apparent that these are very effective in preventing disease in children. Conjugated haemophilus vaccines were introduced into the routine immunization schedules in the UK in Autumn 1992. Meningococcal A and C polysaccharide vaccines, effective for epidemic disease, are only now being developed in a protein conjugated form with the prospect of protecting young children and producing durable immunity. Group B outer membrane-based meningococcal vaccines produce only a low degree of protection and much further work is needed before even the optimum vaccine constituents of this organism can be identified. Vaccines to replace multivalent pneumococcal polysaccharide mixtures are only in the very earliest stages of development.

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Bacterial Capsules Bacterial Vaccines Forecasting Haemophilus Vaccines Humans Immunization Meningitis, Bacterial Meningococcal Vaccines Polysaccharides, Bacterial Streptococcus pneumoniae Journal Article Review

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D M Jones. 1993. Current and future trends in immunization against meningitis.. https://doi.org/10.1093/jac%2F31.suppl_b.93

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